Virus detectives test whole-body scans in search of HIV’s hiding places
To prevent the virus from rebounding after drug therapy, researchers must first map where it lurks in the body.
Antiretroviral drugs have transformed HIV infection from a death sentence to a chronic condition for many people who carry the virus. But because HIV never truly leaves the body, the virus rebounds rapidly if patients stop taking the drugs for even a short time.
Now scientists are trying to figure out how, and where, HIV hides when blood tests show that a person’s viral load is low or undetectable. The location of this reservoir has long been a mystery, but that could soon change. Powerful new techniques are giving researchers an unprecedented look at how HIV travels though the bodies of people and animals — turning up clues to the virus’s hiding places and new targets for future therapies.
By Sara Reardon